Tuesday, August 01, 2006

antipsychotics: more smoke

Further evidence from Lilly (the makers of Zyprexa) on the adverse effects of antipsychotic medications in the elderly from the Journal of Clinial Psychiatry . Six studies were examined for mortality , CVAEs and other adverse effects in the use of olanzapine, risperidone and conventional anti-psychotics . Mortality was found to be significantly higher in olanzapine treated patients (3.5%)than in placebo treated patients ( 1.5%) There was no difference in crude mortality between olanzapine and risperidone and conventional anti-psychotics.

A Review of Treatment-Emergent Adverse Events During Olanzapine Clinical Trials in Elderly Patients With Dementia.

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